吴深基,男,福建尤溪人,甘肃农业大学动物遗传育种与繁殖专业博士研究生,主要从事鱼类体色变异和抗逆胁迫响应的分子机制研究。主持完成省级项目1项和校级项目2项,以第一作者在Aquaculture、International Journal of Biological Macromolecules、Fish & Shellfish Immunology、Ecotoxicology and Environmental Safety、BMC Genomics等国内外期刊发表论文10余篇。
(1)2025年青海省“高端创新人才千人计划”拔尖人才
(1)甘肃省自然科学基金优秀博士生项目:虹鳟体色变异关键miR-495的功能研究(22JR5RA844),4万元,主持,结题。
(2)甘肃农业大学优秀博士学位论文培育项目:虹鳟急慢性低氧胁迫下非编码RNA的筛选、鉴定及其调控机制研究(YB2022001),20万元,主持,结题。
(1) Wu SJ, Huang JQ*, Li YJ, et al. Integrated physiological, whole transcriptomic and functional analysis reveals the regulatory mechanism in the liver of rainbow trout (Oncorhynchus mykiss) in response to short-term and chronic hypoxia stress. Aquaculture, 2024, 593: 741250.
(2) Wu SJ, Huang JQ, Li YJ*, et al. Dynamic and systemic regulatory mechanisms in rainbow trout (Oncorhynchus mykiss) in response to acute hypoxia and reoxygenation stress. Aquaculture, 2023, 572: 739540.
(3) Wu SJ, Huang JQ*, Li YJ, et al. Involvement of miR-495 in the skin pigmentation of rainbow trout (Oncorhynchus mykiss) through the regulation of mc1r. International Journal of Biological Macromolecules, 2024, 254: 127638.
(4) Wu SJ, Huang JQ*, Li YJ, et al. Comparative transcriptomics combined with physiological and functional analysis reveals the regulatory mechanism of rainbow trout (Oncorhynchus mykiss) under acute hypoxia stress. Ecotoxicology and Environmental Safety, 2024, 278: 116347.
(5) Wu SJ, Huang JQ*, Li YJ. A novel hypoxic lncRNA, LOC110520012 sponges miR-206-y to regulate angiogenesis and liver cell proliferation in rainbow trout (Oncorhynchus mykiss) by targeting vegfaa. Ecotoxicology and Environmental Safety, 2024, 280: 116554.
(6) Wu SJ, Huang JQ*, Li YJ. Antiviral effect of miR-206 in rainbow trout (Oncorhynchus mykiss) against infectious hematopoietic necrosis virus infection. Fish & Shellfish Immunology, 2024, 149: 109552.
(7) Wu SJ, Huang JQ*, Li YJ, et al. Integrated analysis of immune parameters, miRNA-mRNA interaction, and immune genes expression in the liver of rainbow trout following infectious hematopoietic necrosis virus infection. Frontiers in Immunology, 2022, 13: 970321.
(8) Wu SJ, Zhao L, Huang JQ*, et al. MiR-330 targeting BCO2 is involved in carotenoid metabolism to regulate skin pigmentation in rainbow trout (Oncorhynchus mykiss). BMC Genomics, 2023, 24: 124.